Wednesday, July 21, 2010

Urine can not replace kidney function tests

Review a number of kidney patients, only urine tests, the results are not abnormal renal function on the view that no problem. In fact, only to see if a urine proteinuria, hematuria and abnormal, and can not fully reflect the kidney function. Some patients with early renal dysfunction, due to loss of protein in urine very little urine has been hardening, loss of filtration function, urine protein but does not appear, urine examination was normal, then those who can not excrete toxins from the kidney to accumulate In the blood, this easy to cover up the false condition.

When kidney damage, the protein may leak into the urine is an early sign of renal damage. Can do at this time as a 24-hour urine protein examination, often accurately reflect the amount of urinary protein loss. This is due to increased glomerular permeability or low molecular weight plasma protein too, or renal tubular epithelial cell injury, weight reduction or loss of absorptive capacity, the protein will be poured into the urine, when more than a heavy tubular produce proteinuria when absorptive capacity. Proteinuria is there more than the normal amount of urine protein, usually take 24-hour urine protein test. 24-hour urine protein in the 0.15 to 0.5 grams as microalbuminuria, between 0.5 to 1 gram of mild proteinuria, 3.5 grams in a moderate proteinuria, severe proteinuria greater than 3.5 grams. If the 24-hour urine protein test results reported sustained protein (ie, within a few weeks there were two positive results), suggesting that patients with chronic kidney disease.

However, the qualitative and quantitative urine protein examination, the diagnosis of kidney disease, a coarse screening test. Kidney damage, because of the difficulties will be excluded creatinine accumulate in the blood to a higher level, therefore, only through a higher level, by Charles serum creatinine, urea nitrogen, can know the extent of kidney damage.

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